Vinnie is the owner of a pop culture memorabilia store and lives in Los Angeles without a care in the world. After his brother and sister-in-law suddenly die six months before the setting of the show, Vinnie finds himself as the legal guardian of his wise-beyond-his-years nephew, Wendell. With a little help from Vinnie's sister, Wilma, and his next-door neighbor, Taryn, Vinnie gets the hang of being a parent. At the same time, Wendell finds himself trying to keep his immature uncle under control.