The series follows the eponymous detectives Alfe (Ben Jones), Roba (also Jones), and Horace (Kyle Kaplan). The trio take up solving, and sometimes creating, the numerous problems that plague their town, Farboro. To their aid is Tux Dog (John DiMaggio), an extremely wealthy dog who helps the Solverz in some of their cases but is just as often the source of their problems. Alfe (pronounced Alfé) is a large, fluffy, fur monster (even though it was suggested that he may be "half-chocolate, half-mutt" in Neon Knome or that he was a man-dog-anteater by creator and voice actor Ben Jones during the 2011 San Diego Comic Con Panel) found and raised by Horace when both were young. He loves devouring large quantities of food, especially pizza and hamburgers, and acts impulsively during missions. Roba, Horace's twin brother and cyborg, is the smartest member of the group, but he suffers from insecurity and anxiety. Horace is the calm and collected leader of the team, usually applying common sense with his detective work and caring after Alfe. Creator Ben Jones was part of the art collective Paper Rad, which consists of comics, music, and video art. He created the “Dogman 99” art style, in which they used juxtaposed images and bright neon colors, combined with primary colors to give their work a distinct lo-fi and underground look. He pitched this idea as "Neon Knome" to Adult Swim in 2008, as was shown in 2010 as part of the Big Über Network Sampling, an online development contest as presented by Burger King. Unfortunately, Adult Swim rejected the show, claiming that the art style was "too mind-blowingly cute" for their lineup, hence why it ended up on Cartoon Network.