Becky (Parker Posey), Gayle (Amy Poehler) and Judi (Rachel Dratch) are a trio of 30-something pals who lead terribly unsophisticated lives. When Becky is asked to accompany her boss's daughter (Amber Tamblyn) to South Padre Island for college spring break, the three see a chance to throw away their geeky personas and party with the cool kids.